Catalog Number:
E45M10732V-2Amount:
50 ulCite ID#:
EN5446887Price:
195$Type:
Mouse Monoclonal AntibodyProduct Description:
LMAN1 mouse monoclonal antibody, Clone 1C5Host:
MouseReactivity:
Human, Monkey, Mouse, RatImmunogen:
Full length human recombinant protein of human LMAN1(NP_005561) produced in Hek293T cell.Target:
LMAN1Clone Number:
Clone 1C5Isotype:
IgG1Purification:
Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)Gene Name:
lectin, mannose binding 1Gene symbol:
LMAN1Gene ID:
3998Swiss-Prot No.:
P49257Function:
Druggable Genome, TransmembraneSummary:
The protein encoded by this gene is a type I integral membrane protein localized in the intermediate region between the endoplasmic reticulum and the Golgi, presumably recycling between the two compartments. The protein is a mannose-specific lectin and is a member of a novel family of plant lectin homologs in the secretory pathway of animal cells. Mutations in the gene are associated with a coagulation defect. Using positional cloning, the gene was identified as the disease gene leading to combined factor V-factor VIII deficiency, a rare, autosomal recessive disorder in which both coagulation factors V and VIII are diminished. [provided by RefSeq]Form:
PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.Concentration:
0.97 mg/mlStorage/Stability:
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.Applications:
WB 1:500~2000, IHC 1:150, FLOW 1:100Synonyms:
ERGIC-53; ERGIC53; F5F8D; FMFD1; gp58; MCFD1; MR60