Catalog Number:
E45M08919V-2Amount:
50 ulCite ID#:
EN5445074Price:
195$Type:
Mouse Monoclonal AntibodyProduct Description:
CK8 (Keratin 8) mouse monoclonal antibody, Clone 1B12Host:
MouseReactivity:
Human, Monkey, Mouse, Rat, DogImmunogen:
Human recombinant protein fragment corresponding to amino acids 91-381 of human CK8 (NP_002264) produced in E.coli.Target:
KRT8Clone Number:
Clone 1B12Isotype:
IgG2bPurification:
Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)Gene Name:
keratin 8Gene symbol:
KRT8Gene ID:
3856Swiss-Prot No.:
P05787Function:
Druggable GenomeSummary:
Keratin 8 is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis.Form:
PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.Concentration:
1 mg/mlStorage/Stability:
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.Applications:
WB 1:2500~5000, IHC 1:50 - 1:150, IF 1:50 - 1:100Synonyms:
CARD2; CK-8; CK8; CYK8; K2C8; K8; KO