Catalog Number:
E45M08634G-1Amount:
100 µlCite ID#:
EN5482208Price:
395$Type:
Rabbit Polyclonal AntibodyHost:
RabbitReactivity:
HImmunogen:
This IFT27 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 157-183 amino acids of human IFT27.Purification:
Affinity chromatography purified.Gene Name:
IFT27Gene ID:
11020Swiss-Prot No.:
Q9BW83Function:
Small GTPase-like component of the intraflagellar transport (IFT) complex B that promotes the exit of the BBSome complex from cilia via its interaction with ARL6 (PubMed:25443296). Not involved in entry of the BBSome complex into cilium. Prevents aggregation of GTP-free ARL6 (PubMed:25443296). Required for hedgehog signaling. Forms a subcomplex within the IFT complex B with IFT25. Its role in intraflagellar transport is mainly seen in tissues rich in ciliated cells such as kidney and testis. Essential for male fertility, spermiogenesis and sperm flagella formation. Plays a role in the early development of the kidney. May be involved in the regulation of ureteric bud initiation (By similarity).Form:
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.Storage/Stability:
For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.Applications:
WBDilution:
WB--1:1000Altername:
Intraflagellar transport protein 27 homolog, Putative GTP-binding protein RAY-like, Rab-like protein 4, IFT27, RABL4, RAYL