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SIGLEC8 Antibody (C-term)
Datasheet   

  • Catalog Number:

    E45M07800G-4

  • Amount:

    50 µl

  • Cite ID#:

    EN5471265

  • Price:

    295$

  • Type:

    Rabbit Polyclonal Antibody

  • Host:

    Rabbit

  • Reactivity:

    H, M

  • Immunogen:

    This SIGLEC8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 373-406 amino acids from the C-terminal region of human SIGLEC8.

  • Purification:

    Affinity chromatography purified.

  • Gene Name:

    SIGLEC8

  • Gene ID:

    27181

  • Swiss-Prot No.:

    Q9NYZ4

  • Function:

    Putative adhesion molecule that mediates sialic-acid dependent binding to red blood cells (PubMed:10856141, PubMed:10625619). Preferentially binds to alpha-2,3-linked sialic acid. Also binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface (PubMed:10625619). Recognizes simultaneously epitopes having a terminal N-acetylneuraminic acid (sialic acid) and an underlying 6-O-sulfated galactose. Preferentially binds to Gal-6- sulfated sialyl-Lewis X glycan epitopes (PubMed:27357658).

  • Summary:

    Tissue Location:
    Expressed specifically on red blood cells namely basophil, mast cells and eosinophils.

  • Form:

    Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

  • Storage/Stability:

    For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

  • Applications:

    WB, IHC-P

  • Dilution:

    WB--1:1000
    IHC-P--1:100~500

  • Altername:

    Sialic acid-binding Ig-like lectin 8, Siglec-8, Sialoadhesin family member 2, SAF-2, SIGLEC8, SAF2

  • Synonyms:

    Sialic acid-binding Ig-like lectin 8, Siglec-8, Sialoadhesin family member 2, SAF-2, SIGLEC8, SAF2

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SIGLEC8 Antibody (C-term) | EnoGene Biotech Co. Ltd