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VDR Antibody
Datasheet   

  • Catalog Number:

    E45M02421G-1
  • Amount:

    100 µl
  • Cite ID#:

    EN5480065
  • Price:

    395$
  • Type:

    Mouse Monoclonal Antibody
  • Host:

    Mouse
  • Reactivity:

    H
  • Immunogen:

    Purified His-tagged VDR protein(Fragment) was used to produced this monoclonal antibody.
  • Purification:

    Affinity chromatography purified.
  • Gene Name:

    VDR
  • Gene ID:

    7421
  • Swiss-Prot No.:

    P11473
  • Function:

    Nuclear receptor for calcitriol, the active form of vitamin D3 which mediates the action of this vitamin on cells (PubMed:28698609, PubMed:16913708, PubMed:15728261, PubMed:10678179). Enters the nucleus upon vitamin D3 binding where it forms heterodimers with the retinoid X receptor/RXR (PubMed:28698609). The VDR-RXR heterodimers bind to specific response elements on DNA and activate the transcription of vitamin D3-responsive target genes (PubMed:28698609). Plays a central role in calcium homeostasis (By similarity).
  • Form:

    Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
  • Storage/Stability:

    For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Applications:

    WB
  • Dilution:

    WB--1:2000
  • Altername:

    Vitamin D3 receptor, VDR,25-dihydroxyvitamin D3 receptor, Nuclear receptor subfamily 1 group I member 1, VDR, NR1I1

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