Catalog Number:
E45M02421G-1Amount:
100 µlCite ID#:
EN5480065Price:
395$Type:
Mouse Monoclonal AntibodyHost:
MouseReactivity:
HImmunogen:
Purified His-tagged VDR protein(Fragment) was used to produced this monoclonal antibody.Purification:
Affinity chromatography purified.Gene Name:
VDRGene ID:
7421Swiss-Prot No.:
P11473Function:
Nuclear receptor for calcitriol, the active form of vitamin D3 which mediates the action of this vitamin on cells (PubMed:28698609, PubMed:16913708, PubMed:15728261, PubMed:10678179). Enters the nucleus upon vitamin D3 binding where it forms heterodimers with the retinoid X receptor/RXR (PubMed:28698609). The VDR-RXR heterodimers bind to specific response elements on DNA and activate the transcription of vitamin D3-responsive target genes (PubMed:28698609). Plays a central role in calcium homeostasis (By similarity).Form:
Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.Storage/Stability:
For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.Applications:
WBDilution:
WB--1:2000Altername:
Vitamin D3 receptor, VDR,25-dihydroxyvitamin D3 receptor, Nuclear receptor subfamily 1 group I member 1, VDR, NR1I1