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ELISA Kits
Mouse Axl/Tyrosine-protein kinase receptor UFO ELISA Kit
Mouse
$907/ 96T
QuantityTotal: $907
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Cite ID#EN5520836
TypeMouse ELISA Kits (Murine)
DescriptionMouse Axl/Tyrosine-protein kinase receptor UFO ELISA Kit is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit designed for the quantitative measurement of Axl in biological samples. Our rigorously validated, ready-to-go Mouse Axl/Tyrosine-protein kinase receptor UFO ELISA Kit use a simple protocol that easily integrates into your current processes, allowing you to rapidly and accurately detect Axl in your samples. Appropriate sample types may include Cell Culture Supernates, Serum, Platelet-poor EDTA Plasma, Platelet-poor Heparin Plasma, Urine.
Precision
Intra-Assay Precision (Precision within an assay): Three samples of known concentration were tested several times on one plate to assess intra-assay precision.
Inter-Assay Precision (Precision between assays): Three samples of known concentration were tested in several separate assays to assess inter-assay precision. Assays were performed by at least two technicians using two lots of components.
Precision
Intra-Assay Precision (Precision within an assay): Three samples of known concentration were tested several times on one plate to assess intra-assay precision.
Inter-Assay Precision (Precision between assays): Three samples of known concentration were tested in several separate assays to assess inter-assay precision. Assays were performed by at least two technicians using two lots of components.
Assay typeSandwich
Detection principleSpectrophotometrical
Sample typeThis immunoassay kit allows for the in vitro quantitative determination in Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids.
Sensitivity15.62 pg/mL
Assay range31.2-2000 pg/mL
Kit componentsAssay Plate, Standard, Sample Diluent, Assay Diluent A&B, Detection Reagent A&B, Wash Buffer, Substrate, Stop Solution.
Other reagents requiredDeionized or distilled water
FunctionReceptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding growth factor GAS6 and which is thus regulating many physiological processes including cell survival, cell proliferation, migration and differentiation. Ligand binding at the cell surface induces dimerization and autophosphorylation of AXL. Following activation by ligand, ALX binds and induces tyrosine phosphorylation of PI3-kinase subunits PIK3R1, PIK3R2 and PIK3R3; but also GRB2, PLCG1, LCK and PTPN11. Other downstream substrate candidates for AXL are CBL, NCK2, SOCS1 and TNS2. Recruitment of GRB2 and phosphatidylinositol 3 kinase regulatory subunits by AXL leads to the downstream activation of the AKT kinase. GAS6/AXL signaling plays a role in various processes such as endothelial cell survival during acidification by preventing apoptosis, optimal cytokine signaling during human natural killer cell development, hepatic regeneration, gonadotropin-releasing hormone neuron survival and migration, platelet activation, or regulation of thrombotic responses. Plays also an important role in inhibition of Toll-like receptors (TLRs)-mediated innate immune response.
FormELISA Kits
SynonymsAdhesion-related kinase,Ark,Ufo
Price907$
Gene NameAxl
Storage/StabilityStore at +4°C. Please refer to protocols.
Conjugated Antibody
This product is also available conjugated. Format: E45K00385-Conjugate. Price: $485 / Size: 100μl.
E45K00385-FITC$485 / 100μlE45K00385-Biotin$485 / 100μlE45K00385-HRP$485 / 100μlE45K00385-AP$485 / 100μlE45K00385-AF350$485 / 100μlE45K00385-AF405M$485 / 100μlE45K00385-AF488$485 / 100μlE45K00385-AF514$485 / 100μlE45K00385-AF532$485 / 100μlE45K00385-AF555$485 / 100μlE45K00385-AF568$485 / 100μlE45K00385-AF405S$485 / 100μlE45K00385-AF405L$485 / 100μlE45K00385-AF546$485 / 100μlE45K00385-AF594$485 / 100μlE45K00385-AF610$485 / 100μlE45K00385-AF635$485 / 100μlE45K00385-AF647$485 / 100μlE45K00385-AF680$485 / 100μlE45K00385-AF700$485 / 100μlE45K00385-AF750$485 / 100μlE45K00385-AF790$485 / 100μlE45K00385-APC$485 / 100μlE45K00385-PE$485 / 100μlE45K00385-Cy3$485 / 100μlE45K00385-Cy5$485 / 100μlE45K00385-Cy5.5$485 / 100μlE45K00385-Cy7$485 / 100μlE45K00385-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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