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ELISA Kits

Mouse Tnfsf11/Tumor necrosis factor ligand superfamily member 11 ELISA Kit

Mouse
O35235
$907/ 96T
Quantity
Total: $907

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Product Information

Cite ID#EN5520793
TypeMouse ELISA Kits (Murine)
DescriptionMouse Tnfsf11/Tumor necrosis factor ligand superfamily member 11 ELISA Kit is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit designed for the quantitative measurement of Tnfsf11 in biological samples. Our rigorously validated, ready-to-go Mouse Tnfsf11/Tumor necrosis factor ligand superfamily member 11 ELISA Kit use a simple protocol that easily integrates into your current processes, allowing you to rapidly and accurately detect Tnfsf11 in your samples. Appropriate sample types may include Cell Culture Supernates, Serum, Platelet-poor EDTA Plasma, Platelet-poor Heparin Plasma, Urine.

Precision
Intra-Assay Precision (Precision within an assay): Three samples of known concentration were tested several times on one plate to assess intra-assay precision.
Inter-Assay Precision (Precision between assays): Three samples of known concentration were tested in several separate assays to assess inter-assay precision. Assays were performed by at least two technicians using two lots of components.
Assay typeSandwich
Detection principleSpectrophotometrical
Sample typeThis immunoassay kit allows for the in vitro quantitative determination in Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids.
Sensitivity7.92 pg/mL
Assay range15.6-1000 pg/mL
Kit componentsAssay Plate, Standard, Sample Diluent, Assay Diluent A&B, Detection Reagent A&B, Wash Buffer, Substrate, Stop Solution.
Other reagents requiredDeionized or distilled water
FunctionCytokine that binds to TNFRSF11B/OPG and to TNFRSF11A/RANK. Osteoclast differentiation and activation factor. Augments the ability of dendritic cells to stimulate naive T-cell proliferation. May be an important regulator of interactions between T-cells and dendritic cells and may play a role in the regulation of the T-cell-dependent immune response. May also play an important role in enhanced bone-resorption in humoral hypercalcemia of malignancy (By similarity). Induces osteoclastogenesis by activating multiple signaling pathways in osteoclast precursor cells, chief among which is induction of long lasting oscillations in the intracellular concentration of Ca (2+) resulting in the activation of NFATC1, which translocates to the nucleus and induces osteoclast-specific gene transcription to allow differentiation of osteoclasts (PubMed:24039232). During osteoclast differentiation, in a TMEM64 and ATP2A2-dependent manner induces activation of CREB1 and mitochondrial ROS generation necessary for proper osteoclast generation (PubMed:23395171, PubMed:26644563).
FormELISA Kits
SynonymsOsteoclast differentiation factor,ODF,Osteoprotegerin ligand,OPGL,Receptor activator of nuclear factor kappa-B ligand,RANKL,TNF-related activation-induced cytokine,TRANCE,CD254,Opgl,Rankl,Trance
Price907$
Gene NameTnfsf11
Storage/StabilityStore at +4°C. Please refer to protocols.
Mouse Tnfsf11/Tumor necrosis factor ligand superfamily member 11 ELISA Kit | EnoGene Biotech Co. Ltd