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ELISA Kits
Mouse Pcsk9/Proprotein convertase subtilisin/kexin type 9 ELISA Kit
Mouse
$907/ 96T
QuantityTotal: $907
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Cite ID#EN5520759
TypeMouse ELISA Kits (Murine)
DescriptionMouse Pcsk9/Proprotein convertase subtilisin/kexin type 9 ELISA Kit is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit designed for the quantitative measurement of Pcsk9 in biological samples. Our rigorously validated, ready-to-go Mouse Pcsk9/Proprotein convertase subtilisin/kexin type 9 ELISA Kit use a simple protocol that easily integrates into your current processes, allowing you to rapidly and accurately detect Pcsk9 in your samples. Appropriate sample types may include Cell Culture Supernates, Serum, Platelet-poor EDTA Plasma, Platelet-poor Heparin Plasma, Urine.
Precision
Intra-Assay Precision (Precision within an assay): Three samples of known concentration were tested several times on one plate to assess intra-assay precision.
Inter-Assay Precision (Precision between assays): Three samples of known concentration were tested in several separate assays to assess inter-assay precision. Assays were performed by at least two technicians using two lots of components.
Precision
Intra-Assay Precision (Precision within an assay): Three samples of known concentration were tested several times on one plate to assess intra-assay precision.
Inter-Assay Precision (Precision between assays): Three samples of known concentration were tested in several separate assays to assess inter-assay precision. Assays were performed by at least two technicians using two lots of components.
Assay typeSandwich
Detection principleSpectrophotometrical
Sample typeThis immunoassay kit allows for the in vitro quantitative determination in Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids.
Sensitivity7.89 pg/mL
Assay range15.6-1000 pg/ml
Kit componentsAssay Plate, Standard, Sample Diluent, Assay Diluent A&B, Detection Reagent A&B, Wash Buffer, Substrate, Stop Solution.
Other reagents requiredDeionized or distilled water
FunctionCrucial player in the regulation of plasma cholesterol homeostasis. Binds to low-density lipid receptor family members: low density lipoprotein receptor (LDLR), very low density lipoprotein receptor (VLDLR), apolipoprotein E receptor (LRP1/APOER) and apolipoprotein receptor 2 (LRP8/APOER2), and promotes their degradation in intracellular acidic compartments. Acts via a non-proteolytic mechanism to enhance the degradation of the hepatic LDLR through a clathrin LDLRAP1/ARH-mediated pathway. May prevent the recycling of LDLR from endosomes to the cell surface or direct it to lysosomes for degradation. Can induce ubiquitination of LDLR leading to its subsequent degradation. Inhibits intracellular degradation of APOB via the autophagosome/lysosome pathway in a LDLR-independent manner. Involved in the disposal of non-acetylated intermediates of BACE1 in the early secretory pathway. Inhibits epithelial Na(+) channel (ENaC)-mediated Na(+) absorption by reducing ENaC surface expression primarily by increasing its proteasomal degradation. Regulates neuronal apoptosis via modulation of LRP8/APOER2 levels and related anti-apoptotic signaling pathways.
FormELISA Kits
SynonymsNeural apoptosis-regulated convertase 1,NARC-1,Proprotein convertase 9,PC9,Subtilisin/kexin-like protease PC9,Narc1
Price907$
Gene NamePcsk9
Storage/StabilityStore at +4°C. Please refer to protocols.
Conjugated Antibody
This product is also available conjugated. Format: E45K00308-Conjugate. Price: $485 / Size: 100μl.
E45K00308-FITC$485 / 100μlE45K00308-Biotin$485 / 100μlE45K00308-HRP$485 / 100μlE45K00308-AP$485 / 100μlE45K00308-AF350$485 / 100μlE45K00308-AF405M$485 / 100μlE45K00308-AF488$485 / 100μlE45K00308-AF514$485 / 100μlE45K00308-AF532$485 / 100μlE45K00308-AF555$485 / 100μlE45K00308-AF568$485 / 100μlE45K00308-AF405S$485 / 100μlE45K00308-AF405L$485 / 100μlE45K00308-AF546$485 / 100μlE45K00308-AF594$485 / 100μlE45K00308-AF610$485 / 100μlE45K00308-AF635$485 / 100μlE45K00308-AF647$485 / 100μlE45K00308-AF680$485 / 100μlE45K00308-AF700$485 / 100μlE45K00308-AF750$485 / 100μlE45K00308-AF790$485 / 100μlE45K00308-APC$485 / 100μlE45K00308-PE$485 / 100μlE45K00308-Cy3$485 / 100μlE45K00308-Cy5$485 / 100μlE45K00308-Cy5.5$485 / 100μlE45K00308-Cy7$485 / 100μlE45K00308-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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