Catalog Number:
E45H39534M5Amount:
20 ugCite ID#:
EN5441965Price:
785$Type:
Recombinant ProteinsResearch Field:
Metabolic pathways, Pyrimidine metabolismProduct Description:
Recombinant protein of human uracil phosphoribosyltransferase (FUR1) homolog (S. cerevisiae) (UPRT)Protein length:
Recombinant protein was produced with GoldORF clone, [GH34961V]. Click on the GoldORF clone link to view cDNA and protein sequences.Expression Host:
HEK293TSpecies:
HumanMolecular Weight:
33.6 kDaGene symbol:
UPRTGene ID:
139596mRNA Refseq:
NM_145052Protein Refseq:
NP_659489Swiss-Prot No.:
Q96BW1, A8KAF9Chromosome location:
Xq13.3Pathway:
Metabolic pathways, Pyrimidine metabolismFunction:
Druggable GenomeSummary:
This gene encodes uracil phosphoribosyltransferase, which catalyzes the conversion of uracil and 5-phosphoribosyl-1-R-diphosphate to uridine monophosphate (UMP). This reaction is an important part of nucleotide metabolism, specifically the pyrimidine salvage pathway. The enzyme localizes to the nucleus and cytoplasm. The protein is a potential target for rational design of drugs to treat parasitic infections and cancer. [provided by RefSeq, Nov 2009]Form:
LiquidConcentration:
>50 ug/mL as determined by microplate BCA methodPurity:
> 80% as determined by SDS-PAGE and Coomassie blue stainingStorage/Stability:
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.Storage Buffer:
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerolSynonyms:
FUR1; UPP