Catalog Number:
E45H38067M5Amount:
20 ugCite ID#:
EN5440499Price:
785$Type:
Recombinant ProteinsProduct Description:
Recombinant protein of human cancer susceptibility candidate 3 (CASC3)Protein length:
Recombinant protein was produced with GoldORF clone, [GH38359V]. Click on the GoldORF clone link to view cDNA and protein sequences.Expression Host:
HEK293TSpecies:
HumanMolecular Weight:
76.1 kDaGene symbol:
CASC3Gene ID:
22794mRNA Refseq:
NM_007359Protein Refseq:
NP_031385Swiss-Prot No.:
O15234Chromosome location:
17q21.1Summary:
The product of this gene is a core component of the exon junction complex (EJC), a protein complex that is deposited on spliced mRNAs at exon-exon junctions and functions in nonsense-mediated mRNA decay (NMD). The encoded protein binds RNA and interacts with two other EJC core components. It is predominantly located in the cytoplasm, but shuttles into the nucleus where it localizes to nuclear speckles. [provided by RefSeq, Jul 2008]Form:
LiquidConcentration:
>50 ug/mL as determined by microplate BCA methodPurity:
> 80% as determined by SDS-PAGE and Coomassie blue stainingStorage/Stability:
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.Storage Buffer:
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerolSynonyms:
BTZ; MLN51