Ankyrin brain (ANK2) (NM_020977) Human Recombinant Protein
Datasheet
Catalog Number:
E45H36187M5Amount:
20 ugCite ID#:
EN5438619Price:
785$Type:
Recombinant ProteinsProduct Description:
Recombinant protein of human ankyrin 2, neuronal (ANK2), transcript variant 2Protein length:
Recombinant protein was produced with GoldORF clone, [GH43824V]. Click on the GoldORF clone link to view cDNA and protein sequences.Expression Host:
HEK293TSpecies:
HumanMolecular Weight:
205.6 kDaGene symbol:
ANK2Gene ID:
287mRNA Refseq:
NM_020977Protein Refseq:
NP_066187Swiss-Prot No.:
Q01484Chromosome location:
4q25-q26Function:
Druggable GenomeSummary:
This gene encodes a member of the ankyrin family of proteins that link the integral membrane proteins to the underlying spectrin-actin cytoskeleton. Ankyrins play key roles in activities such as cell motility, activation, proliferation, contact and the maintenance of specialized membrane domains. Most ankyrins are typically composed of three structural domains: an amino-terminal domain containing multiple ankyrin repeats; a central region with a highly conserved spectrin binding domain; and a carboxy-terminal regulatory domain which is the least conserved and subject to variation. The protein encoded by this gene is required for targeting and stability of Na/Ca exchanger 1 in cardiomyocytes. Mutations in this gene cause long QT syndrome 4 and cardiac arrhythmia syndrome. Multiple transcript variants encoding different isoforms have been described. [provided by RefSeq, Dec 2011]Form:
LiquidConcentration:
>50 ug/mL as determined by microplate BCA methodPurity:
> 80% as determined by SDS-PAGE and Coomassie blue stainingStorage/Stability:
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.Storage Buffer:
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerolSynonyms:
ANK-2; brank-2; CFAP87; FAP87; LQT4
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Catalog Number
- Amount:20 ug
- Price:785$
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