Catalog Number:
E45H31501E1Amount:
50 ugCite ID#:
EN5426811Price:
553$Type:
Recombinant ProteinsResearch Field:
Systemic lupus erythematosusProduct Description:
Purified recombinant protein of Human histone cluster 1, H2bk (HIST1H2BK), full length, with N-terminal HIS tag, expressed in E. coli, 50ugProtein length:
A DNA sequence encoding human full-length HIST1H2BKExpression Host:
E. coliSpecies:
HumanMolecular Weight:
13.7 kDaGene symbol:
H2BC12Gene ID:
85236mRNA Refseq:
NM_080593Protein Refseq:
NP_542160Swiss-Prot No.:
O60814, A0A024RCL8Chromosome location:
6p22.1Pathway:
Systemic lupus erythematosusSummary:
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-dependent histone that is a member of the histone H2B family. The protein encoded is an antimicrobial protein with antibacterial and antifungal activity. Two transcripts that encode the same protein have been identified for this gene, which is found in the histone microcluster on chromosome 6p21.33. [provided by RefSeq, Aug 2015]Form:
LiquidConcentration:
>50 ug/mL as determined by microplate BCA methodPurity:
> 80% as determined by SDS-PAGE and Coomassie blue stainingStorage/Stability:
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.Storage Buffer:
25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1 % Sarkosyl.Synonyms:
H2B/S; H2BFAiii; H2BFT; H2BK; HIST1H2BK