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H2BC12 (NM_080593) Human Recombinant Protein
Datasheet   

  • Catalog Number:

    E45H31501E1
  • Amount:

    50 ug
  • Cite ID#:

    EN5426811
  • Price:

    553$
  • Type:

    Recombinant Proteins
  • Research Field:

    Systemic lupus erythematosus
  • Product Description:

    Purified recombinant protein of Human histone cluster 1, H2bk (HIST1H2BK), full length, with N-terminal HIS tag, expressed in E. coli, 50ug
  • Protein length:

    A DNA sequence encoding human full-length HIST1H2BK
  • Expression Host:

    E. coli
  • Species:

    Human
  • Molecular Weight:

    13.7 kDa
  • Gene symbol:

    H2BC12
  • Gene ID:

    85236
  • mRNA Refseq:

    NM_080593
  • Protein Refseq:

    NP_542160
  • Swiss-Prot No.:

    O60814, A0A024RCL8
  • Chromosome location:

    6p22.1
  • Pathway:

    Systemic lupus erythematosus
  • Summary:

    Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-dependent histone that is a member of the histone H2B family. The protein encoded is an antimicrobial protein with antibacterial and antifungal activity. Two transcripts that encode the same protein have been identified for this gene, which is found in the histone microcluster on chromosome 6p21.33. [provided by RefSeq, Aug 2015]
  • Form:

    Liquid
  • Concentration:

    >50 ug/mL as determined by microplate BCA method
  • Purity:

    > 80% as determined by SDS-PAGE and Coomassie blue staining
  • Storage/Stability:

    Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
  • Storage Buffer:

    25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1 % Sarkosyl.
  • Synonyms:

    H2B/S; H2BFAiii; H2BFT; H2BK; HIST1H2BK

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H2BC12 (NM_080593) Human Recombinant Protein | EnoGene Biotech Co. Ltd