KDM4D (NM_018039) Human Recombinant Protein

KDM4D (NM_018039) Human Recombinant Protein
Datasheet

Catalog Number:
E45H30618E6
Amount:
50 ug
Cite ID#:
EN5425930
Price:
553$
Type:
Recombinant Proteins
Product Description:
Purified recombinant protein of Human lysine (K)-specific demethylase 4D (KDM4D), full length, with N-terminal GST and C-terminal His tag, expressed in E. coli, 50ug
Protein length:
A DNA sequence encoding human full-length KDM4D
Expression Host:
E. coli
Species:
Human
Molecular Weight:
86.4 kDa
Gene symbol:
KDM4D
Gene ID:
55693
mRNA Refseq:
NM_018039
Protein Refseq:
NP_060509
Swiss-Prot No.:
Q6B0I6
Chromosome location:
11q21
Summary:
Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Demethylates both di- and trimethylated H3 'Lys-9' residue, while it has no activity on monomethylated residues. Demethylation of Lys residue generates formaldehyde and succinate.[UniProtKB/Swiss-Prot Function]
Form:
Liquid
Concentration:
>50 ug/mL as determined by microplate BCA method
Purity:
> 80% as determined by SDS-PAGE and Coomassie blue staining
Storage/Stability:
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Storage Buffer:
50mM Tris, pH8.0, 8M Urea.
Synonyms:
JMJD2D

KDM4D (NM_018039) Human Recombinant Protein
Datasheet