Catalog Number:
E45H30414E1Amount:
50 ugCite ID#:
EN5425726Price:
555$Type:
Recombinant ProteinsProduct Description:
Purified recombinant protein of Human ligand of numb-protein X 1 (LNX1), transcript variant 2, Met260-Val528, with N-terminal His tag, expressed in E. coli, 50ugProtein length:
A DNA sequence encoding the region(Met260-Val528) of LNX1Expression Host:
E. coliSpecies:
HumanMolecular Weight:
29.7 kDaGene symbol:
LNX1Gene ID:
84708mRNA Refseq:
NM_032622Protein Refseq:
NP_116011Swiss-Prot No.:
Q8TBB1Chromosome location:
4q12Function:
Druggable GenomeSummary:
This gene encodes a membrane-bound protein that is involved in signal transduction and protein interactions. The encoded product is an E3 ubiquitin-protein ligase, which mediates ubiquitination and subsequent proteasomal degradation of proteins containing phosphotyrosine binding (PTB) domains. This protein may play an important role in tumorogenesis. Alternatively spliced transcript variants encoding distinct isoforms have been described. A pseudogene, which is located on chromosome 17, has been identified for this gene. [provided by RefSeq, Jul 2008]Form:
LiquidConcentration:
>50 ug/mL as determined by microplate BCA methodPurity:
> 80% as determined by SDS-PAGE and Coomassie blue stainingStorage/Stability:
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.Storage Buffer:
25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1% Sarkosyl.Synonyms:
LNX; MPDZ; PDZRN2