Catalog Number:
E45H30359E1Amount:
50 ugCite ID#:
EN5425671Price:
555$Type:
Recombinant ProteinsProduct Description:
Purified recombinant protein of Human coilin (COIL), Met1-Lys220, with N-terminal His tag, expressed in E. coli, 50ugProtein length:
A DNA sequence encoding the region(Met1-Lys220) of COILExpression Host:
E. coliSpecies:
HumanMolecular Weight:
24.9 kDaGene symbol:
COILGene ID:
8161mRNA Refseq:
NM_004645Protein Refseq:
NP_004636Swiss-Prot No.:
P38432Chromosome location:
17q22Function:
Stem cell - PluripotencySummary:
The protein encoded by this gene is an integral component of Cajal bodies (also called coiled bodies). Cajal bodies are nuclear suborganelles of varying number and composition that are involved in the post-transcriptional modification of small nuclear and small nucleolar RNAs. The N-terminus of the coilin protein directs its self-oligomerization while the C-terminus influences the number of nuclear bodies assembled per cell. Differential methylation and phosphorylation of coilin likely influences its localization among nuclear bodies and the composition and assembly of Cajal bodies. This gene has pseudogenes on chromosome 4 and chromosome 14. [provided by RefSeq, Jul 2008]Form:
LiquidConcentration:
>50 ug/mL as determined by microplate BCA methodPurity:
> 80% as determined by SDS-PAGE and Coomassie blue stainingStorage/Stability:
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.Storage Buffer:
50mM Tris, 8M Urea, pH8.0.Synonyms:
CLN80; p80-coilin