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Coilin (COIL) (NM_004645) Human Recombinant Protein
Datasheet   

  • Catalog Number:

    E45H30359E1
  • Amount:

    50 ug
  • Cite ID#:

    EN5425671
  • Price:

    555$
  • Type:

    Recombinant Proteins
  • Product Description:

    Purified recombinant protein of Human coilin (COIL), Met1-Lys220, with N-terminal His tag, expressed in E. coli, 50ug
  • Protein length:

    A DNA sequence encoding the region(Met1-Lys220) of COIL
  • Expression Host:

    E. coli
  • Species:

    Human
  • Molecular Weight:

    24.9 kDa
  • Gene symbol:

    COIL
  • Gene ID:

    8161
  • mRNA Refseq:

    NM_004645
  • Protein Refseq:

    NP_004636
  • Swiss-Prot No.:

    P38432
  • Chromosome location:

    17q22
  • Function:

    Stem cell - Pluripotency
  • Summary:

    The protein encoded by this gene is an integral component of Cajal bodies (also called coiled bodies). Cajal bodies are nuclear suborganelles of varying number and composition that are involved in the post-transcriptional modification of small nuclear and small nucleolar RNAs. The N-terminus of the coilin protein directs its self-oligomerization while the C-terminus influences the number of nuclear bodies assembled per cell. Differential methylation and phosphorylation of coilin likely influences its localization among nuclear bodies and the composition and assembly of Cajal bodies. This gene has pseudogenes on chromosome 4 and chromosome 14. [provided by RefSeq, Jul 2008]
  • Form:

    Liquid
  • Concentration:

    >50 ug/mL as determined by microplate BCA method
  • Purity:

    > 80% as determined by SDS-PAGE and Coomassie blue staining
  • Storage/Stability:

    Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
  • Storage Buffer:

    50mM Tris, 8M Urea, pH8.0.
  • Synonyms:

    CLN80; p80-coilin

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Coilin (COIL) (NM_004645) Human Recombinant Protein | EnoGene Biotech Co. Ltd