Phospho-RNA polymerase II CTD repeat YSPTSPS (Ser5) Recombinant Rabbit mAb

Phospho-RNA polymerase II CTD repeat YSPTSPS (Ser5) Recombinant Rabbit mAb
Datasheet

Catalog Number:
E43S43293
Amount:
100ul
Cite ID#:
EN5621018
Price:
275$
Swiss-Prot No.:
P24928
Host:
Rabbit
Reactivity:
Human, Mouse, Rat
Applications:
WB,IHC,ICC/IF,FC,IP
Recommended Dilutions:
WB: 1:1000
IHC: 1:100
ICC/IF: 1:100
FC: 1:20
IP: 1:20
Background:
This gene encodes the largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a carboxy terminal domain composed of heptapeptide repeats that are essential for polymerase activity. These repeats contain serine and threonine residues that are phosphorylated in actively transcribing RNA polymerase. In addition, this subunit, in combination with several other polymerase subunits, forms the DNA binding domain of the polymerase, a groove in which the DNA template is transcribed into RNA. [provided by RefSeq, Jul 2008]
Formulation:
Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
Purification:
Affinity Purification
Storage/Stability:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity:
IgG
Molecular Weight:
250 kDa
Altername:
RPB1; RPO2; POLR2; POLRA; RPBh1; RPOL2; RpIILS; hsRPB1; hRPB220
Immunogen:
A synthetic phosphopeptide corresponding to residues surrounding Ser5 of human RNA polymerase II CTD repeat YSPTSPS
Conjugate:
Unconjugated
Modification:
Phosphorylated