World supplier of antibodies, antigens and kits since 2007
2019-nCoV & Monkeypox
Recombinant 2019-nCoV Spike Protein (C-6His)
$395/
QuantityTotal: $395
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Form Or Antibody
Form of AntibodyName:Recombinant 2019-nCoV Spike Protein (C-6His)
Derived From:
Human Cells
Derived From:
Human Cells
Product Information
DescriptionRecombinant 2019-nCoV Spike Protein is produced by our Mammalian Expi293 expression system.
Accession:
QHD43416.1
Accession:
QHD43416.1
Names(Known as):2019-nCov S protein; 2019-nCoV Spike glycoprotein; 2019-nCoV S glycoprotein
Mol Mass:
77kDa
Mol Mass:
77kDa
PurityGreater than 95% as determined by reducing SDS-PAGE.
FormulationSupplied as a 0.2 μM filtered solution of PBS, pH7.4.
Storage/StabilityProtein solution should be stored at ≤ -20°C.
PurificationAffinity purification chromatography.
Immunoreactivity:
N.A.
Immunoreactivity:
N.A.
Immunogen, calibrator or standard.
BackgroundProtein S (PROS1) is glycoprotein and expressed in many cell types supporting its reported involvement in multiple biological processes that include coagulation, apoptosis, cancer development and progression, and the innate immune response. Known receptors bind S1 are ACE2, angiotensin-converting enzyme 2, DPP4, CEACAM etc. The spike (S) glycoprotein of coronaviruses is known to be essential in the binding of the virus to the host cell at the advent of the infection process. Most notable is severe acute respiratory syndrome (SARS). The severe acute respiratory syndrome-coronavirus (SARS-CoV) spike (S) glycoprotein alone can mediate the membrane fusion required for virus entry and cell fusion. It is also a major immunogen and a target for entry inhibitors. It's been reported that 2019-nCoV can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
Tris-Bis PAGE of Recombinant 2019-nCoV Spike Protein.
Binding data of recombinant 2019-nCoV Spike Protein (C-6His) with ACE2 receptor.
Conjugated Antibody
This product is also available conjugated. Format: E42020T1-Conjugate. Price: $485 / Size: 100μl.
E42020T1-FITC$485 / 100μlE42020T1-Biotin$485 / 100μlE42020T1-HRP$485 / 100μlE42020T1-AP$485 / 100μlE42020T1-AF350$485 / 100μlE42020T1-AF405M$485 / 100μlE42020T1-AF488$485 / 100μlE42020T1-AF514$485 / 100μlE42020T1-AF532$485 / 100μlE42020T1-AF555$485 / 100μlE42020T1-AF568$485 / 100μlE42020T1-AF405S$485 / 100μlE42020T1-AF405L$485 / 100μlE42020T1-AF546$485 / 100μlE42020T1-AF594$485 / 100μlE42020T1-AF610$485 / 100μlE42020T1-AF635$485 / 100μlE42020T1-AF647$485 / 100μlE42020T1-AF680$485 / 100μlE42020T1-AF700$485 / 100μlE42020T1-AF750$485 / 100μlE42020T1-AF790$485 / 100μlE42020T1-APC$485 / 100μlE42020T1-PE$485 / 100μlE42020T1-Cy3$485 / 100μlE42020T1-Cy5$485 / 100μlE42020T1-Cy5.5$485 / 100μlE42020T1-Cy7$485 / 100μlE42020T1-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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