World supplier of antibodies, antigens and kits since 2007
2019-nCoV & Monkeypox
human IL-17, His tag
$395/
QuantityTotal: $395
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Product Information
ExpressionHEK293FTag: C-His
Mol Mass:17kDa
Mol Mass:17kDa
PurityGreater than 95% as determined by reducing SDS-PAGE.
PurificationNi column
Form Or Antibody
Form of AntibodyTris-Gly
BackgroundInterleukin-17 is a potent pro-inflammatory cytokine produced by activated memory T cells. There are at least six members of the IL-17 family in humans and in mice. As IL-17 shares properties with IL-1 and TNFalpha, it may induce joint inflammation and bone and cartilage destruction. This cytokine is found in synovial fluids of patients with rheumatoid arthritis, and produced by rheumatoid arthritis synovium. It increases IL-6 production, induces collagen degradation and decreases collagen synthesis by synovium and cartilage and proteoglycan synthesis in cartilage. IL-17 is also able to increase bone destruction and reduce its formation. Blocking of interleukin-17 with specific inhibitors provides a protective inhibition of cartilage and bone degradation.
Storage/StabilityStore at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
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