Product Information
Clone NumberDM25
IsotypeRabbit IgG
Molecular Weight141kDa
Recommended DilutionsELISA 1/5000-10000
FormulationLiquid
PreservativePreservative: 0.1%Procline 300Constituents: 50%Glycerol; PBS, pH 7.4; 0.1%BSA
Ship DescriptionIce pack
Sample usageResearch use only
Expression HostCHO cell
All Names
AlternameSARS-CoV-2 Spike S2
ImmunogenRecombinant SARS-CoV-2 Spike S2 protein (686-1213) produced by using E. coli
PurificationPurified from cell culture supernatant by affinity chromatography
Storage/StabilityStore at -20°C for 15 months (Avoid repeated freezing and thawing)
BackgroundSARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) also known as Covid19 (2019 Novel Coronavirus) is a virus that causes illnesses ranging from the common cold to severe diseases. The spike protein is a type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which accounts for recognizing the cell surface receptor, ACE2. S2 contains basic elements needed for the membrane fusion. Recent publications indicate that S1-RBD domain can induce virus neutralizing-antibody and T cell response.