Product Information
Clone NumberDM22
IsotypeRabbit IgG
Molecular Weight45kDa
Recommended DilutionsELISA 1/5000-10000
FormulationLiquid
PreservativePreservative: 0.1%Procline 300Constituents: 50%Glycerol; PBS, pH 7.4; 0.1%BSA
Ship DescriptionIce pack
Sample usageResearch use only
Expression HostCHO cell
All Names
AlternameSARS-CoV-2 Nucleocapsid
ImmunogenRecombinant SARS-CoV-2 Nucleocapsid (Met1-Ala 419) produced by using E. coli
PurificationPurified from cell culture supernatant by affinity chromatography
Storage/StabilityStore at -20°C for 15 months (Avoid repeated freezing and thawing)
BackgroundCoronavirus contain most of nucleocapsid protein. Coronavirus nucleoproteins (N proteins) localize to the cytoplasm and the nucleolus, a subnuclear structure, in both virus-infected primary cells and in cells transfected with plasmids that express N protein. The nucleolus is the site of ribosome biogenesis and sequesters cell cycle regulatory complexes. Two of the major components of the nucleolus are fibrillarin and nucleolin. These proteins are involved in nucleolar assembly and ribosome biogenesis and act as chaperones for the import of proteins into the nucleolus. Regarding of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is a tool for diagnostic.