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PROTAK™ FKBP12 PROTAC dTAG-13
$1550/ 1mg
QuantityTotal: $1550
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Product Information
CAS No.2064175-41-1
FormulaC57H68N4O15
M.W.1049.17
SolubilitySoluble in DMSO
Storage/StabilityStore at -20°C
BackgroundFKBP12 PROTAC dTAG-13 (dTAG-13) is a PROTAC-based heterobifunctional degrader. FKBP12 PROTAC dTAG-13 (dTAG-13) is a degrader of FKBP12F36V with expression of FKBP12F36V in-frame with a protein of interest. FKBP12 PROTAC dTAG-13 (dTAG-13) also is a selective degrader of BET bromodomain transcriptional co-activator BRD4 by bridging BET bromodomains to an E3 ubiquitin ligase CRBN.
Nabet B, et al. The dTAG system for immediate and target-specific protein degradation. Nat Chem Biol. 2018 May;14(5):431-441.
Nabet B, et al. The dTAG system for immediate and target-specific protein degradation. Nat Chem Biol. 2018 May;14(5):431-441.
Price1550$
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