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PROTAK™ K-Ras ligand-Linker Conjugate 5
$2160/ 100mg
QuantityTotal: $2160
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
CAS No.2378261-85-7
FormulaC42H59N7O8
M.W.789.96
SolubilitySoluble in DMSO
Storage/StabilityStore at -20°C
BackgroundK-Ras ligand-Linker Conjugate 5 incorporates a ligand for K-Ras recruiting moiety, and a PROTAC linker, which recruit E3 ligases (such as VHL, CRBN, MDM2, and IAP). K-Ras ligand-Linker Conjugate 5 can be used in the synthesis of PROTAC K-Ras Degrader-1 (HY-129523), which is potent PROTAC K-Ras degrader that exhibits ≥70% degradation efficacy in SW1573 cells.
CREW, Andrew P., et al. MODULATORS OF PROTEOLYSIS AND ASSOCIATED METHODS OF USE.
PROTAK™ is a registered trademark of EnoGene.
CREW, Andrew P., et al. MODULATORS OF PROTEOLYSIS AND ASSOCIATED METHODS OF USE.
PROTAK™ is a registered trademark of EnoGene.
Price2160$
Number: E31P39225 PROTAK™ K-Ras ligand-Linker Conjugate 5
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