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PROTAK™ iRucaparib-AP6
$1320/ 1mg
Specification
QuantityTotal: $1320
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
FormulaC46H55FN6O11
M.W.886.96
SolubilitySoluble in DMSO
Storage/StabilityStore at -20°C
BackgroundiRucaparib-AP6 is a highly efficient and specific PARP1 degrader based on Rucaparib by using thePROTAC approach. iRucaparib-AP6, a non-trapping PARP1 degrader, blocks both the catalytic activity and scaffolding effects of PARP1.
Wang S, et al. Uncoupling of PARP1 trapping and inhibition using selective PARP1 degradation.Nat Chem Biol. 2019 Dec;15(12):1223-1231.
Wang S, et al. Uncoupling of PARP1 trapping and inhibition using selective PARP1 degradation.Nat Chem Biol. 2019 Dec;15(12):1223-1231.
Price1320$
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