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PROTAK™ N-Boc-4-pentyne-1-amine

E31P38966-1DatasheetCOAMSDS
$160/ 10mg
Specification
Quantity
Total: $160

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Product Information

CAS No.151978-50-6
FormulaC10H17NO2
M.W.183.25
SolubilitySoluble in DMSO
Storage/StabilityStore at -20°C
BackgroundN-Boc-4-pentyne-1-amine is a PROTAC linker, which refers to the alkyl chain composition. N-Boc-4-pentyne-1-amine can be used in the synthesis of the PROTAC MG-277 (HY-130122).
Yang J, et al. Simple Structural Modifications Converting a Bona fide MDM2 PROTAC Degrader into a Molecular Glue Molecule: A Cautionary Tale in the Design of PROTAC Degraders. J Med Chem. 2019 Oct 21.
Price160$