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PROTAK™ Thalidomide-NH-PEG2-C2-NH2 TFA
$1320/ 1mg
Specification
QuantityTotal: $1320
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Product Information
CAS No.2097509-36-7
FormulaC21H25F3N4O8
M.W.518.44
SolubilitySoluble in DMSO
Storage/StabilityStore at -20°C
BackgroundThalidomide-O-amido-PEG3-C2-NH2 TFA is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and 2-unit PEG linker used in PROTAC technology.
Wang Z, et al. Proteolysis Targeting Chimeras for the Selective Degradation of Mcl-1/Bcl-2 Derived from Nonselective Target Binding Ligands. J Med Chem. 2019 Sep 12;62(17):8152-8163.
Wang Z, et al. Proteolysis Targeting Chimeras for the Selective Degradation of Mcl-1/Bcl-2 Derived from Nonselective Target Binding Ligands. J Med Chem. 2019 Sep 12;62(17):8152-8163.
Price1320$
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