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PROTAK™Thalidomide-O- PEG2- propargyl
$140/ 5mg
Specification
QuantityTotal: $140
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Product Information
CAS No.2098487-52-4
FormulaC20H20N2O7
M.W.400.38
SolubilitySoluble in DMSO
Storage/StabilityStore at -20°C
BackgroundThalidomide-O-PEG2-propargyl (E3 ligase Ligand-Linker Conjugates 32) is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and 2-unit PEG linker used in PROTAC technology.
Wurz RP, et al. A "Click Chemistry Platform" for the Rapid Synthesis of Bispecific Molecules for Inducing Protein Degradation. J Med Chem. 2018 Jan 25;61(2):453-461.
Wurz RP, et al. A "Click Chemistry Platform" for the Rapid Synthesis of Bispecific Molecules for Inducing Protein Degradation. J Med Chem. 2018 Jan 25;61(2):453-461.
Price140$
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