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PROTAK™ FAK ligand-Linker Conjugate 1
$1320/ 1mg
Specification
QuantityTotal: $1320
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
CAS No.2307461-45-4
FormulaC25H28F3N5O6S
M.W.583.58
SolubilitySoluble in DMSO
Storage/StabilityStore at -20°C
BackgroundFAK ligand-Linker Conjugate 1 incorporates a ligand for FAK, and a PROTAC linker, which recruit E3 ligases (such as VHL, CRBN, MDM2, and IAP). FAK ligand-Linker Conjugate 1 can be extensively used for PROTAC-mediated protein degradation.
Cromm PM, et al. Addressing Kinase-Independent Functions of Fak via PROTAC-Mediated Degradation. J Am Chem Soc. 2018 Dec 12;140(49):17019-17026.
Cromm PM, et al. Addressing Kinase-Independent Functions of Fak via PROTAC-Mediated Degradation. J Am Chem Soc. 2018 Dec 12;140(49):17019-17026.
Price1320$
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