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PROTAK™ Thalidomide-O-amido-C3-NH2 (TFA)
$150/ 5mg
Specification
QuantityTotal: $150
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Product Information
CAS No.2022182-58-5
FormulaC20H21F3N4O8
M.W.502.4
SolubilitySoluble in DMSO
Storage/StabilityStore at -20°C
BackgroundThalidomide-O-amido-C3-NH2 TFA is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.
Lohbeck J, et al. Practical synthesis of a phthalimide-based Cereblon ligand to enable PROTAC development. Bioorg Med Chem Lett. 2016 Nov 1;26(21):5260-5262.
Lohbeck J, et al. Practical synthesis of a phthalimide-based Cereblon ligand to enable PROTAC development. Bioorg Med Chem Lett. 2016 Nov 1;26(21):5260-5262.
Price150$
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