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PROTAK™ PEG6-(CH2CO2H)2
$240/ 50mg
Specification
QuantityTotal: $240
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Product Information
CAS No.77855-76-6
FormulaC14H26O10
M.W.354.35
SolubilitySoluble in DMSO
Storage/StabilityStore at -20°C
BackgroundPEG6-(CH2CO2H)2 is a symmetric PEG PROTAC linker, for the synthesis of Homo-PROTACs which is bivalent small-molecule dimerizers of the VHL E3 ubiquitin ligase to induce self-degradation[1]. PEGs
Maniaci C, et al. Homo-PROTACs: bivalent small-molecule dimerizers of the VHL E3 ubiquitin ligase to induce self-degradation. Nat Commun. 2017 Oct 10;8(1):830.
Maniaci C, et al. Homo-PROTACs: bivalent small-molecule dimerizers of the VHL E3 ubiquitin ligase to induce self-degradation. Nat Commun. 2017 Oct 10;8(1):830.
Price240$
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