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PROTAK™ E3 ligase Ligand- Linker Conjugates 30 TFA
$840/ 100mg
Specification
QuantityTotal: $840
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
FormulaC23H29F3N4O9
M.W.562.49
SolubilitySoluble in DMSO
Storage/StabilityStore at -20°C
BackgroundE3 ligase Ligand-Linker Conjugates 30 TFA incorporates a cereblon (CRBN) ligand for the E3 ubiquitin ligase, and a PROTAC linker. E3 ligase Ligand-Linker Conjugates 30 TFA can be used to design PROTAC degrader. Cereblon
Li Y, et al. Discovery of MD-224 as a First-in-Class, Highly Potent, and Efficacious Proteolysis Targeting Chimera Murine Double Minute 2 Degrader Capable of Achieving Complete and Durable Tumor Regression. J Med Chem. 2019 Jan 24;62(2):448-466.
Li Y, et al. Discovery of MD-224 as a First-in-Class, Highly Potent, and Efficacious Proteolysis Targeting Chimera Murine Double Minute 2 Degrader Capable of Achieving Complete and Durable Tumor Regression. J Med Chem. 2019 Jan 24;62(2):448-466.
Price840$
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