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PROTAK™ BI-4464

E31P34488-1DatasheetCOAMSDS
$1080/ 5mg
Specification
Quantity
Total: $1080

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Product Information

CAS No.1227948-02-8
FormulaC28H28F3N5O4
M.W.555.55
SolubilityDMSO : 16.67 mg/mL (30.01 mM; Need ultrasonic)
Storage/StabilityStore at -20°C
BackgroundBI-4464 is a highly selective ATP competitive inhibitor of PTK2/FAK, with an IC50 of 17 nM. A PTK2 ligand for PROTAC[1]. IC50: 17 nM (PTK2/FAK).
Popow J, et al. Highly Selective PTK2 Proteolysis Targeting Chimeras to Probe Focal Adhesion Kinase Scaffolding Functions. J Med Chem. 2019 Mar 14;62(5):2508-2520.
Price1080$