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PROTAK™ N33-TEG-COOH (N3-TEG-COOH)

$120/ 100mg
Quantity
Total: $120

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

Product Information

CAS No.201467-81-4
Purity>98.00%
FormulaC10H19N3O6
M.W.277.27
SolubilityDMSO : ≥ 100 mg/mL (360.66 mM)
Storage/StabilityStore at -20°C
BackgroundN33-TEG-COOH is a PROTAC linker containing four polyethylene glycol (PEG) units.N33-TEG-COOH is a long linker extracted from Reference PMID: 26035625, Compound 7. A PROTAC is a heterobifunctional compound that contains two ligands connected by a linker unit. One ligand binds an E3 ubiquitin ligase protein, while the other ligand binds to the target protein of interest, thereby bringing the ligase and the target in close proximity]. Zengerle M, et al. Selective Small Molecule Induced Degradation of the BET Bromodomain Protein BRD4. ACS Chem Biol. 2015 Aug 21;10(8):1770-7.
Price120$