Catalog Number:
E28PP1404Amount:
100ulApplications:
WBReactivity:
HumanPrice:
255$Gene Name:
MAP2K7 JNKK2 MEK7 MKK7 PRKMK7 SKK4Gene ID:
5609Swiss-Prot No.:
O14733Specificity:
This antibody detects endogenous levels of Human MKK7 (phospho-Ser271 or Thr275)Formulation:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.Source:
RabbitDilution:
WB 1:1000-2000Purification:
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.Storage/Stability:
-20°C/1 yearAltername:
Dual specificity mitogen-activated protein kinase kinase 7 (MAP kinase kinase 7) (MAPKK 7) (EC 2.7.12.2) (JNK-activating kinase 2) (MAPK/ERK kinase 7) (MEK 7) (Stress-activated protein kinase kinase 4) (SAPK kinase 4) (SAPKK-4) (SAPKK4) (c-Jun N-terminal kinase kinase 2) (JNK kinase 2) (JNKK 2)Molecular Weight:
47KDBackground:
mitogen-activated protein kinase kinase 7(MAP2K7) Homo sapiens The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically activates MAPK8/JNK1 and MAPK9/JNK2, and this kinase itself is phosphorylated and activated by MAP kinase kinase kinases including MAP3K1/MEKK1, MAP3K2/MEKK2,MAP3K3/MEKK5, and MAP4K2/GCK. This kinase is involved in the signal transduction mediating the cell responses to proinflammatory cytokines, and environmental stresses. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014],