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HNRPAB Rabbit Polyclonal Antibody (N-term)
Datasheet   

  • Catalog Number:

    E28PB4531

  • Amount:

    100ul

  • Price:

    255$

  • Altername:

    Heterogeneous nuclear ribonucleoprotein A/B, hnRNP A/B, APOBEC1-binding protein 1, ABBP-1, HNRNPAB, ABBP1, HNRPAB

  • Applications:

    IHC-P, IF, WB

  • Reactivity:

    Human

  • Formulation:

    Purified polyclonal antibody supplied in PBS with 0.09% (W/V) New type preservative N. This antibody is purified through a protein A column, followed by peptide affinity purification.

  • Human Gene Id:

    NP_004490.2;NP_112556.2

  • Swiss-Prot No.:

    Q99729

  • Specificity:

    This HNRPAB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human HNRPAB.

  • Recommended Dilutions:

    WB~~1:1000;IHC-P~~1:100~500;IF~~1:10~50

  • Predicted Molecular Weight:

    36kDa

  • Form of Antibody:

    Liquid

  • Storage/Stability:

    Shipped at 4°C. Upon delivery aliquot and store at -20°C for one year. Avoid freeze/thaw cycles.

  • Source:

    Rabbit

  • Isotype:

    Rabbit IgG

  • Background:

    This gene belongs to the subfamily of ubiquitously
    expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The
    hnRNPs are produced by RNA polymerase II and are components of the
    heterogeneous nuclear RNA (hnRNA) complexes. They are associated
    with pre-mRNAs in the nucleus and appear to influence pre-mRNA
    processing and other aspects of mRNA metabolism and transport.
    While all of the hnRNPs are present in the nucleus, some seem to
    shuttle between the nucleus and the cytoplasm. The hnRNP proteins
    have distinct nucleic acid binding properties. The protein encoded
    by this gene, which binds to one of the components of the
    multiprotein editosome complex, has two repeats of quasi-RRM (RNA
    recognition motif) domains that bind to RNAs.

  • Tissue Expression:

    Ubiquitous.

  • Cellular localization:

    Nucleus. Cytoplasm. Note=Localized in cytoplasmic mRNP granules containing untranslated mRNAs

  • Function:

    Binds single-stranded RNA. Has a high affinity for G-rich and U-rich regions of hnRNA. Also binds to APOB mRNA transcripts around the RNA editing site.

  • HNRPAB Antibody (N-term) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the HNRPAB antibody detected the HNRPAB protein (arrow).

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  • Amount:100ul
  • Price:255$

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HNRPAB Rabbit Polyclonal Antibody (N-term) | EnoGene Biotech Co. Ltd