Catalog Number:
E28PB4010Amount:
100ulPrice:
255$Altername:
mRNA-capping enzyme, HCAP1, HCE, Polynucleotide 5'-triphosphatase, mRNA 5'-triphosphatase, TPase, mRNA guanylyltransferase, GTP--RNA guanylyltransferase, GTase, RNGTT, CAP1AApplications:
WB, FCReactivity:
Human, Rat, MouseHuman Gene Id:
NP_003791.3Swiss-Prot No.:
O60942Specificity:
This RNGTT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 489-516 amino acids from the C-terminal region of human RNGTT.Recommended Dilutions:
WB~~1:1000;FC~~1:10~50Predicted Molecular Weight:
69kDaForm of Antibody:
LiquidStorage/Stability:
Shipped at 4°C. Upon delivery aliquot and store at -20°C for one year. Avoid freeze/thaw cycles.Isotype:
Rabbit IgGBackground:
RNGTT is a bifunctional mRNA-capping enzyme exhibiting RNA 5'-triphosphatase activity in the N-terminal part and mRNA guanylyltransferase activity in the C-terminal part. The protein catalyzes the first two steps of cap formation: by removing the gamma-phosphate from the 5'-triphosphate end of nascent mRNA to yield a diphosphate end, and by transferring the gmp moiety of GTP to the 5'-diphosphate terminus.Tissue Expression:
Isoform 1 and isoform 4 (at a lesser extent) are expressed in cerebrum, cerebellum, thyroid, lung, heart, liver, kidney, spleen, large intestine, testis, skin and muscleCellular localization:
Nucleus.