Catalog Number:
E28M6716Amount:
100ulCite ID#:
EN5544151Price:
295$Applications:
WB,IHC,ICC/IFReactivity:
Human,Mouse,RatType:
Rabbit Monoclonal AntibodyStorage/Stability:
Shipped at 4°C. Upon delivery aliquot and store at -20°C for one year. Avoid freeze/thaw cycles.Altername:
CMAVM; GAP; p120GAP; p120RASGAP; PKWS; RASA; RASA1; RasGAP;Gene Name:
RASA1Protein Name:
GAP, RASAFormulation:
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.Human Gene Id:
5921Swiss-Prot No.:
P20936Immunogen:
A synthetic peptide of human RASA1Recommended Dilutions:
WB: 1:1000 IHC: 1:20 ICC/IF: 1:50Molecular Weight:
140kDaPredicted Molecular Weight:
116kDaForm of Antibody:
LiquidIsotype:
Rabbit IgGTissue Expression:
In placental villi, detected only in the trophoblast layer (cytotrophoblast and syncytiotrophoblast). Not detected in stromal, endothelial or Hofbauer cells (at protein level)Cellular localization:
Cytoplasm.Description:
Inhibitory regulator of the Ras-cyclic AMP pathway. Stimulates the GTPase of normal but not oncogenic Ras p21.Function:
Inhibitory regulator of the Ras-cyclic AMP pathway. Stimulates the GTPase of normal but not oncogenic Ras p21; this stimulation may be further increased in the presence of NCK1.