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MMP17 (19A10) Rabbit Monoclonal Antibody
Datasheet   

  • Catalog Number:

    E28M5642
  • Amount:

    100ul
  • Cite ID#:

    EN5543092
  • Price:

    295$
  • Applications:

    WB,IHC,ICC/IF
  • Reactivity:

    Human,Mouse,Rat
  • Type:

    Rabbit Monoclonal Antibody
  • Storage/Stability:

    Shipped at 4°C. Upon delivery aliquot and store at -20°C for one year. Avoid freeze/thaw cycles.
  • Altername:

    MMP 17; Mmp17; MT MMP4; MT-MMP 4; MT4 MMP; MT4-MMP; MT4MMP; MTMMP4;
  • Gene Name:

    MMP17
  • Protein Name:

    MT4MMP
  • Formulation:

    Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
  • Human Gene Id:

    4326
  • Swiss-Prot No.:

    Q9ULZ9
  • Immunogen:

    A synthetic peptide of human MT4-MMP
  • Recommended Dilutions:

    WB: 1:1000 IHC: 1:100 ICC/IF: 1:20-1:100
  • Molecular Weight:

    63kDa
  • Predicted Molecular Weight:

    67kDa
  • Form of Antibody:

    Liquid
  • Isotype:

    Rabbit IgG
  • Tissue Expression:

    Expressed in brain, leukocytes, colon, ovary testis and breast cancer. Expressed also in many transformed and non- transformed cell types
  • Cellular localization:

    [Isoform Long]: Cell membrane; Lipid-anchor, GPI- anchor; Extracellular side. Secreted, extracellular space, extracellular matrix
  • Description:

    Endopeptidase that degrades various components of the extracellular matrix, such as fibrin. May be involved in the activation of membrane-bound precursors of growth factors or inflammatory mediators, such as tumor necrosis factor-alpha. May also be involved in tumoral process.
  • Function:

    Endopeptidase that degrades various components of the extracellular matrix, such as fibrin. May be involved in the activation of membrane-bound precursors of growth factors or inflammatory mediators, such as tumor necrosis factor-alpha. May also be involved in tumoral process. Cleaves pro-TNF-alpha at the '74-Ala-|-Gln-75' site. Not obvious if able to proteolytically activate progelatinase A. Does not hydrolyze collagen types I, II, III, IV and V, gelatin, fibronectin, laminin, decorin nor alpha1-antitrypsin.
  • Western blot analysis of MMP17 expression in HeLa cell lysate.

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MMP17 (19A10) Rabbit Monoclonal Antibody | EnoGene Biotech Co. Ltd