Catalog Number:
E28M5642Amount:
100ulCite ID#:
EN5543092Price:
295$Applications:
WB,IHC,ICC/IFReactivity:
Human,Mouse,RatType:
Rabbit Monoclonal AntibodyStorage/Stability:
Shipped at 4°C. Upon delivery aliquot and store at -20°C for one year. Avoid freeze/thaw cycles.Altername:
MMP 17; Mmp17; MT MMP4; MT-MMP 4; MT4 MMP; MT4-MMP; MT4MMP; MTMMP4;Gene Name:
MMP17Protein Name:
MT4MMPFormulation:
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.Human Gene Id:
4326Swiss-Prot No.:
Q9ULZ9Immunogen:
A synthetic peptide of human MT4-MMPRecommended Dilutions:
WB: 1:1000 IHC: 1:100 ICC/IF: 1:20-1:100Molecular Weight:
63kDaPredicted Molecular Weight:
67kDaForm of Antibody:
LiquidIsotype:
Rabbit IgGTissue Expression:
Expressed in brain, leukocytes, colon, ovary testis and breast cancer. Expressed also in many transformed and non- transformed cell typesCellular localization:
[Isoform Long]: Cell membrane; Lipid-anchor, GPI- anchor; Extracellular side. Secreted, extracellular space, extracellular matrixDescription:
Endopeptidase that degrades various components of the extracellular matrix, such as fibrin. May be involved in the activation of membrane-bound precursors of growth factors or inflammatory mediators, such as tumor necrosis factor-alpha. May also be involved in tumoral process.Function:
Endopeptidase that degrades various components of the extracellular matrix, such as fibrin. May be involved in the activation of membrane-bound precursors of growth factors or inflammatory mediators, such as tumor necrosis factor-alpha. May also be involved in tumoral process. Cleaves pro-TNF-alpha at the '74-Ala-|-Gln-75' site. Not obvious if able to proteolytically activate progelatinase A. Does not hydrolyze collagen types I, II, III, IV and V, gelatin, fibronectin, laminin, decorin nor alpha1-antitrypsin.