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UBE2L3 (C-term) Rabbit pAb
Datasheet   

  • Catalog Number:

    E2620600

  • Amount:

    100ul

  • Price:

    225$

  • Swiss-Prot No.:

    P68036

  • Altername:

    UBE2L3

  • Storage/Stability:

    Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

  • Immunogen:

    This UBE2L3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 106-135 amino acids from the C-terminal region of human UBE2L3.

  • Purification:

    Affinity purified

  • Reactivity:

    Human,Mouse,Rat

  • Other Names:

    E2-F1; L-UBC; UBCH7; UbcM4

  • Cellular localization:

    Cytoplasm, Nucleus

  • Relevance:

    Ubiquitin-conjugating enzyme E2 that specifically acts with HECT-type and RBR family E3 ubiquitin-protein ligases. Does not function with most RING-containing E3 ubiquitin-protein ligases because it lacks intrinsic E3-independent reactivity with lysine: in contrast, it has activity with the RBR family E3 enzymes, such as PARK2 and ARIH1, that function like function like RING-HECT hybrids. Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-11'-linked polyubiquitination. Involved in the selective degradation of short-lived and abnormal proteins. Down- regulated during the S-phase it is involved in progression through the cell cycle. Regulates nuclear hormone receptors transcriptional activity. May play a role in myelopoiesis.

  • Source:

    Rabbit

  • Antibody type:

    Polyclonal antibody

  • Isotype:

    Rabbit Ig

  • Molecular Weight:

    H=18,14;M=18 KDa

  • Preservative:

    PBS with 0.09% (W/V) sodium azide, pH7.3.

  • Recommended Dilutions:

    WB:1:1000;IHC-P:1:25

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UBE2L3 (C-term) Rabbit pAb | EnoGene Biotech Co. Ltd