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WB IHC
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Product Information
Host SpeciesRabbit
ClonalityPolyclonal
Species reactivityHu
SpecificityThe antibody detects endogenous levels of total HMGCS2 protein.
Target NameHMGCS2
SDS-PAGE MW57kd
Concentration2.5mg/ml
FormulationRabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
Application DetailsWestern blotting: 1:200-1:1000,Immunohistochemistry: 1:50-1:200
PurificationAntigen affinity purification.
ImmunogenDescription:Synthetic peptide corresponding to a region derived from internal residues of human 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)
Other NamesHMCS2; HMG-CoA synthase; HMGCS2;Accession No.:Swiss-Prot#: P54868NCBI Gene ID: 3158Gene Accssion: NP_005509
Storage/StabilityStore at -20°C
BackgroundThe protein encoded by this gene belongs to the HMG-CoA synthase family. It is a mitochondrial enzyme that catalyzes the first reaction of ketogenesis, a metabolic pathway that provides lipid-derived energy for various organs during times of carbohydrate deprivation, such as fasting. Mutations in this gene are associated with HMG-CoA synthase deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Immunohistochemical analysis of paraffin-embedded Human gastric cancer tissue using HMGCS2 Antibody (E2620490) at dilution 1/40.
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