SRRM1 Rabbit pAb | EnoGene Biotech Co. Ltd

SRRM1 Rabbit pAb
Datasheet

Catalog Number:
E2511282
Amount:
100ul
Price:
225$
Swiss-Prot No.:
Q8IYB3
Altername:
SRRM1
Storage/Stability:
Store at -20°C. Avoid freeze / thaw cycles.
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-160 of human SRRM1 (NP_005830.2).
Purification:
Affinity purified
Reactivity:
Human,Mouse
Other Names:
160-KD; POP101; SRM160
Cellular localization:
Nucleus, Spliceosome
Relevance:
Part of pre- and post-splicing multiprotein mRNP complexes. Involved in numerous pre-mRNA processing events. Promotes constitutive and exonic splicing enhancer (ESE)-dependent splicing activation by bridging together sequence-specific (SR family proteins, SFRS4, SFRS5 and TRA2B/SFRS10) and basal snRNP (SNRP70 and SNRPA1) factors of the spliceosome. Stimulates mRNA 3'-end cleavage independently of the formation of an exon junction complex. Binds both pre-mRNA and spliced mRNA 20-25 nt upstream of exon-exon junctions. Binds RNA and DNA with low sequence specificity and has similar preference for either double- or single-stranded nucleic acid substrates.
Source:
Rabbit
Antibody type:
Polyclonal antibody
Isotype:
Rabbit IgG
Molecular Weight:
117kDa
Preservative:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Recommended Dilutions:
WB 1:500 - 1:1000(Optimal dilutions should be determined by the end user)

SRRM1 Rabbit pAb
Datasheet