Catalog Number:
E2503595Amount:
100ulPrice:
225$Swiss-Prot No.:
Q92608Altername:
DOCK2Storage/Stability:
Store at 4°C. Avoid freeze / thaw cycles.Immunogen:
A synthetic peptide of human DOCK2Purification:
Affinity purifiedReactivity:
HumanOther Names:
IMD40Cellular localization:
Cytoplasm, Cytoskeleton, MembraneRelevance:
Involved in cytoskeletal rearrangements required for lymphocyte migration in response of chemokines. Activates RAC1 and RAC2, but not CDC42, by functioning as a guanine nucleotide exchange factor (GEF), which exchanges bound GDP for free GTP. May also participate in IL2 transcriptional activation via the activation of RAC2.Source:
RabbitAntibody type:
Polyclonal antibodyIsotype:
Rabbit IgGMolecular Weight:
240kDaPreservative:
Store PBS with 0.02% sodium azide, pH7.3.Recommended Dilutions:
WB 1:500 - 1:1000(Optimal dilutions should be determined by the end user)