AOX1 Rabbit pAb | EnoGene Biotech Co. Ltd

AOX1 Rabbit pAb
Datasheet

Catalog Number:
E2503586
Amount:
100ul
Price:
225$
Swiss-Prot No.:
Q06278
Altername:
AOX1
Storage/Stability:
Store at -20°C. Avoid freeze / thaw cycles.
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 340-590 of human AOX1 (NP_001150.3).
Purification:
Affinity purified
Reactivity:
Human,Mouse,Rat
Other Names:
AO; AOH1
Cellular localization:
Cytoplasm
Relevance:
Oxidase with broad substrate specificity, oxidizing aromatic azaheterocycles, such as N1-methylnicotinamide, N-methylphthalazinium and phthalazine, as well as aldehydes, such as benzaldehyde, retinal, pyridoxal, and vanillin. Plays a key role in the metabolism of xenobiotics and drugs containing aromatic azaheterocyclic substituents. Participates in the bioactivation of prodrugs such as famciclovir, catalyzing the oxidation step from 6-deoxypenciclovir to penciclovir, which is a potent antiviral agent. Is probably involved in the regulation of reactive oxygen species homeostasis. May be a prominent source of superoxide generation via the one-electron reduction of molecular oxygen. Also may catalyze nitric oxide (NO) production via the reduction of nitrite to NO with NADH or aldehyde as electron donor. May play a role in adipogenesis.
Source:
Rabbit
Antibody type:
Polyclonal antibody
Isotype:
Rabbit IgG
Molecular Weight:
170kDa
Preservative:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Recommended Dilutions:
WB 1:500 - 1:2000(Optimal dilutions should be determined by the end user)

AOX1 Rabbit pAb
Datasheet