Catalog Number:
E2502364Amount:
100ulPrice:
225$Swiss-Prot No.:
Q16695Altername:
HIST3H3Storage/Stability:
Store at -20°C. Avoid freeze / thaw cycles.Immunogen:
A synthetic methylated peptide corresponding to residues surrounding K36 of human histone H3Purification:
Affinity purifiedReactivity:
Human,Mouse,Rat,A wide range of other speciesOther Names:
H3t; H3.4; H3/g; H3FTCellular localization:
Chromosome, Nucleosome core, NucleusRelevance:
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.Source:
RabbitAntibody type:
Polyclonal antibodyIsotype:
Rabbit IgGMolecular Weight:
16kDaPreservative:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.Recommended Dilutions:
WB 1:500 - 1:2000; IHC 1:50 - 1:200; IF 1:50 - 1:200; IP 1:50 - 1:200; ChIP 1:20 - 1:100; CHIPseq 1:20 - 1:100(Optimal dilutions should be determined by the end user)