Catalog Number:
E2500690Amount:
100ulPrice:
225$Swiss-Prot No.:
O75143Altername:
ATG13Storage/Stability:
Store at -20°C. Avoid freeze / thaw cycles.Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 281-480 of human ATG13 (NP_055556.2).Purification:
Affinity purifiedReactivity:
Human,Mouse,RatOther Names:
KIAA0652; PARATARG8Cellular localization:
CytoplasmRelevance:
Autophagy factor required for autophagosome formation and mitophagy. Target of the TOR kinase signaling pathway that regulates autophagy through the control of the phosphorylation status of ATG13 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex. Through its regulation of ULK1 activity, plays a role in the regulation of the kinase activity of mTORC1 and cell proliferation.Source:
RabbitAntibody type:
Polyclonal antibodyIsotype:
Rabbit IgGMolecular Weight:
70kDaPreservative:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.Recommended Dilutions:
WB 1:500 - 1:2000; IHC 1:50 - 1:200; IF 1:50 - 1:200(Optimal dilutions should be determined by the end user)