World supplier of antibodies, antigens and kits since 2007
Other Products
Smad2/3 Rabbit pAb
$255/ 100ul
QuantityTotal: $255
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Price255$
Antibody typePolyclonal Antibody
Product Information
IsotypeIgG
Clone Number-
UniPort summary FunctionReceptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD2/SMAD4 complex, activates transcription. May act as a tumor suppressor in colorectal carcinoma. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator.
Recommended DilutionsWB: 1/500-1/1000 IF: 1/50-1/200 IP: 1/20 FC: 1/50-1/100 ChIP: 1/20
Molecular WeightCalculated MW: 52 kDa; Observed MW: 52,60 kDa
Product TypePrimary Antibody
PurificationAffinity Purified
Gene NameSMAD2
Other NamesJV18; MADH2; MADR2; JV18-1; hMAD-2; hSMAD2
BackgroundThe protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways.
ImmunogenRecombinant protein of human Smad2
Gene ID4087
Storage/StabilityStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Form Or Antibody
Form of Antibody50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
All Names
AlternameSMAD2; MADH2; MADR2; Mothers against decapentaplegic homolog 2; MAD homolog 2; Mothers against DPP homolog 2; JV18-1; Mad-related protein 2; hMAD-2; SMAD family member 2; SMAD 2; Smad2; hSMAD2
Categories by research area
Categories by product type
- Antibodies
- Primary Antibodies
- Tag antibodies
- Internal control antibodies
- Pathological (Immunohistochemistry, IHC) antibodies
- Cell Signal Transduction Research Antibodies
- Secondary Antibody
- Antibody Sampler Kits
- ELISA Kits
- Recombinant Proteins
- Fluorescence Reagents
- Signal Inhibitors and Activators
- Transfection Reagent
- Cell biology kits
- Overexpression Cell Lines
- Cell Lysates
- Purification Resins
- 2019-nCoV & Monkeypox