Catalog Number:
E2220249Amount:
100ulPrice:
225$Swiss-Prot No.:
Q09472Altername:
EP300Storage/Stability:
Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.Immunogen:
Purified recombinant fragment of EP300 expressed in E. Coli.Purification:
Ascitic fluidReactivity:
HumanOther Names:
p300; KAT3BBackground:
EP300: E1A binding protein p300. This gene encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein. This gene has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF. Defects in this gene are a cause of Rubinstein-Taybi syndrome and may also play a role in epithelial cancer.Gene ID:
2033Cellular localization:
Chromosome, Cytoplasm, NucleusSource:
MouseAntibody type:
Monclonal antibodyIsotype:
Mouse IgG1Preservative:
Ascitic fluid containing 0.03% sodium azide.Recommended Dilutions:
WB: 1/500 - 1/2000; IHC: N/A; ICC: N/A; FCM: N/A; Elisa: 1/10000Clone Number:
7D8A6