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EP300 Mouse mAb
Datasheet   

  • Catalog Number:

    E2220249
  • Amount:

    100ul
  • Price:

    225$
  • Swiss-Prot No.:

    Q09472
  • Altername:

    EP300
  • Storage/Stability:

    Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Immunogen:

    Purified recombinant fragment of EP300 expressed in E. Coli.
  • Purification:

    Ascitic fluid
  • Reactivity:

    Human
  • Other Names:

    p300; KAT3B
  • Background:

    EP300: E1A binding protein p300. This gene encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein. This gene has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF. Defects in this gene are a cause of Rubinstein-Taybi syndrome and may also play a role in epithelial cancer.
  • Gene ID:

    2033
  • Cellular localization:

    Chromosome, Cytoplasm, Nucleus
  • Source:

    Mouse
  • Antibody type:

    Monclonal antibody
  • Isotype:

    Mouse IgG1
  • Preservative:

    Ascitic fluid containing 0.03% sodium azide.
  • Recommended Dilutions:

    WB: 1/500 - 1/2000; IHC: N/A; ICC: N/A; FCM: N/A; Elisa: 1/10000
  • Clone Number:

    7D8A6

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EP300 Mouse mAb | EnoGene Biotech Co. Ltd