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BMI1 Antibody
Datasheet
Catalog Number:
E220113-2Amount:
100ulBackground:
Mouse monoclonal IgG toBMI1Gene ID:
NM_005180.5Immunogen:
Recombinant fragment of human BMI1(C-terminus).Reactivity:
HumanRecommended Dilutions:
ELISA: 1/15000 - 1/20000. WB: 1/100-1/2000.Cellular localization:
NucleusRelevance:
The Bmi1 oncogene induces telomerase activity and immortalizes human mammary epithelial cells. Bmi1 extends the replicative life span of human fibroblasts by suppressing the p16-dependent senescence pathway. Polycomb group (PcG) genes are involved in the maintenance of cellular memory through epigenetic chromatin modifications. Among the PcG genes, Bmi1 plays a central role in the inheritance of stemness, and its forced expression promotes HSC self-renewal.Purity:
Protein G-Sepharose affinity purifiedForm of Antibody:
LiquidPreservative:
0.02% Sodium Azide and 50% glycerol. 1% BSA, PBS, pH7.4.Storage/Stability:
Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
- BMI1(C-terminus) antibody (E220113) at 1/2000 dilution interacts with recombinant BMI1 protein with a DsbA tag. Predicted band size: 48KDa. Observed band size: 48KDa.
Price:
225$Research Area:
Autophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells
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Catalog Number
- Amount:100ul
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