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AKT1 Antibody
Datasheet
Catalog Number:
E220062-2Amount:
100ulBackground:
Mouse monoclonal IgG to AKT1Gene ID:
NM_001014432.1Immunogen:
Recombinant fragment of Human AKT1 (C-terminus).Reactivity:
Hu
Tested applicationsRecommended Dilutions:
. ELISA: 1/5000 - 1/20000. WB: 1/100-1/2000.Cellular localization:
cytoplasmRelevance:
Akt, also referred to as PKB or Rac, plays a critical role in controlling survival and apoptosis. This protein kinase is activated by insulin and various growth and survival factors to function in a wortmannin-sensitive pathway involving PI3 kinase. Akt is activated by phospholipid binding and activation loop phosphorylation at Thr308 by PDK1 and by phosphorylation within the carboxy terminus at Ser473. Akt promotes cell survival by inhibiting apoptosis by phosphorylating and inactivating several targets. LY294002 is a specific PI3 kinase inhibitor.Purity:
Protein G-Sepharose affinity purifiedForm of Antibody:
LiquidPreservative:
0.02% Sodium Azide and 50% glycerol, 1% BSA, PBS, pH7.4.Storage/Stability:
Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
- AKT1 antibody (E220062) at 1/1000 dilution. K562 whole cell lysate 40ug/Lane. Predicted band size: 56KDa. Observed band size: 65KDa.
Price:
225$Research Area:
Autophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem CellsPurification:
Affinity purified
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Catalog Number
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