Catalog Number:
E220014-2Amount:
100ulBackground:
Mouse monoclonal IgG to USP7Gene ID:
NM_003470.2Immunogen:
Recombinant fragment of Human USP7 (N-terminus).Reactivity:
HuRecommended Dilutions:
. ELISA: 1/5000 - 1/20000. WB: 1/100-1/2000.Cellular localization:
NucleusRelevance:
USP7 strongly stabilizes p53 even in the presence of excess MDM2, and induces p53-dependent cell growth repression and apoptosis. USP7 has an intrinsic enzymatic activity that specifically de-ubiquitinates p53 both in vivo and in vitro. This protein may function as a tumor suppressor in vivo through the stabilization of p53. It is also known that USP7 interacts with herpesvirus 1 trans-acting transcriptional protein ICP0/VMW110 and Epstein-Barr virus EBNA1.Purity:
Protein G-Sepharose affinity purifiedForm of Antibody:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.Preservative:
0.02% Sodium Azide and 50% glycerol, 1%BSA, PBS, pH7.4.Storage/Stability:
Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
Price:
225$Research Area:
Autophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem CellsPurification:
Affinity purifiedCatalog Number:
E011009-1Amount:
50μg/50μlReactivity:
Human, Mouse, RatApplications:
IHC: 1:50~1:100Swiss-Prot No.:
P60484Price:
145$
Catalog Number:
E011009-2Amount:
100μg/100μlReactivity:
Human, Mouse, RatApplications:
IHC: 1:50~1:100Swiss-Prot No.:
P60484Price:
225$
Catalog Number:
E011013-1Amount:
50μg/50μlReactivity:
Human, Mouse, RatApplications:
WB: 1:500~1:1000 IF:1:100~1:200Swiss-Prot No.:
Q04206Price:
145$
Catalog Number:
E011013-2Amount:
100μg/100μlReactivity:
Human, Mouse, RatApplications:
WB: 1:500~1:1000 IF:1:100~1:200Swiss-Prot No.:
Q04206Price:
225$
Catalog Number:
E011020-1Amount:
50μg/50μlReactivity:
HumanApplications:
IF:1:100~1:200Swiss-Prot No.:
Q04864Price:
145$