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SOCS3 Antibody
Datasheet   

  • Catalog Number:

    E220003-2

  • Amount:

    100ul

  • Background:

    Mouse monoclonal IgG to SOCS3

  • Gene ID:

    NM_003955.3

  • Immunogen:

    Recombinant fragment of Human SOCS3 (N-terminus).

  • Reactivity:

    Hu
    Tested applications

  • Recommended Dilutions:

    . ELISA: 1/5000 - 1/20000. WB: 1/100-1/2000.

  • Relevance:

    SOCS3 is an SH2-containing protein that binds to the activation loop of Janus kinases, inhibiting kinase activity and thereby suppressing cytokine signaling. It is a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. The expression of the SOCS3 gene is induced by various cytokines, including IL6, IL10, and interferon (IFN)-gamma. Studies of the mouse counterpart of the SOCS3 gene suggested this gene is involved in the negative regulation of fetal liver hematopoiesis, and placental development.

  • Purity:

    Protein G-Sepharose affinity purified.

  • Form of Antibody:

    Liquid

  • Preservative:

    0.02% Sodium Azide and 50% glycerol, 1% BSA, PBS, pH7.4.

  • Storage/Stability:

    Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.

  • SOCS3 antibody (E220003) at 1/500 dilution. Mouse muscle tissue 30ug/lane. Predicted band size: 27Kda. Observed band size: 45Kda.

  • Price:

    225$

  • Research Area:

    Autophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells

  • Purification:

    Affinity purified

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Catalog Number

  • Amount:100ul
  • Price:225$

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